Filamentous hemagglutinin of Bordetella bronchiseptica is required for efficient establishment of tracheal colonization.

@article{Cotter1998FilamentousHO,
  title={Filamentous hemagglutinin of Bordetella bronchiseptica is required for efficient establishment of tracheal colonization.},
  author={Peggy Cotter and Ming H. Yuk and Suneel Mattoo and Brian J. Akerley and J S Boschwitz and David A. Relman and Jeff Miller},
  journal={Infection and immunity},
  year={1998},
  volume={66 12},
  pages={5921-9}
}
Adherence to ciliated respiratory epithelial cells is considered a critical early step in Bordetella pathogenesis. For Bordetella pertussis, the etiologic agent of whooping cough, several factors have been shown to mediate adherence to cells and cell lines in vitro. These putative adhesins include filamentous hemagglutinin (FHA), fimbriae, pertactin, and pertussis toxin. Determining the precise roles of each of these factors in vivo, however, has been difficult, due in part to the lack of… CONTINUE READING

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