Corpus ID: 14684318

Filament turnover is essential for continuous long range contractile flow in a model actomyosin cortex

@article{McFadden2016FilamentTI,
  title={Filament turnover is essential for continuous long range contractile flow in a model actomyosin cortex},
  author={William M. McFadden and Patrick M. McCall and Edwin M. Munro},
  journal={arXiv: Subcellular Processes},
  year={2016}
}
  • William M. McFadden, Patrick M. McCall, Edwin M. Munro
  • Published 2016
  • Biology, Physics
  • arXiv: Subcellular Processes
  • In this paper, we develop and analyze a minimal model for a 2D network of cross-linked actin filaments and myosin motors, representing the cortical cytoskeleton of eukaryotic cells. We implement coarse-grained representations of force production by myosin motors and stress dissipation through an effective cross-link friction and filament turnover. We use this model to characterize how the sustained production of active stress, and the steady dissipation of elastic stress, depend individually on… CONTINUE READING
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