Filaggrin repeat number polymorphism is associated with a dry skin phenotype

@article{Ginger2005FilaggrinRN,
  title={Filaggrin repeat number polymorphism is associated with a dry skin phenotype},
  author={Rebecca S. Ginger and Sarah Blachford and Julie Rowland and Matthew J Rowson and Clive R. Harding},
  journal={Archives of Dermatological Research},
  year={2005},
  volume={297},
  pages={235-241}
}
Profilaggrin is a key epidermal protein, critical for the generation and maintenance of the stratum corneum barrier. It is encoded by a gene located in the epidermal differentiation complex of Chromosome 1q21 and is composed of multiple filaggrin repeats connected by highly conserved linker peptides. Within the human population the number of filaggrin repeats encoded by this gene varies between 10, 11 or 12 repeats. Using a PCR-based approach we have determined individual profilaggrin… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
27 Citations
25 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Stratum corneum moisturising factors

  • CR Harding, IR Scott
  • 2002
3 Excerpts

Scott IR , Dry skin , moisturization and corneodesmolysis

  • CR Harding, A Watkinsion, AV Rawlings
  • Int J Cosmet Sci
  • 2000

Saliva: a convenient source of DNA for analysis of bi-allelic polymorphisms of FCc receptor III B (CD16

  • Van Schie RCAA, ME Wilson
  • J Immunol Methods
  • 1997
2 Excerpts

Similar Papers

Loading similar papers…