Fil1, a G-protein α-subunit that acts upstream of cAMP and is essential for dimorphic switching in haploid cells of Ustilago hordei

@article{Lichter1997Fil1AG,
  title={Fil1, a G-protein α-subunit that acts upstream of cAMP and is essential for dimorphic switching in haploid cells of Ustilago hordei},
  author={Amnon Lichter and Dallice Mills},
  journal={Molecular and General Genetics MGG},
  year={1997},
  volume={256},
  pages={426-435}
}
A constitutive mutation, fil1, that causes filamentous growth in the haplophase of the dimorphic smut fungus Ustilago hordei, was previously shown to be genetically associated with a 50-kb deletion within a 940-kb chromosome. Physiological studies suggested that a gene that functions upstream of adenylyl cyclase was deleted in the mutant. Representational difference analysis of isolated chromosomes was used to obtain deletion-specific DNA probes and corresponding genomic cosmid clones… CONTINUE READING