Fighting infections with vitamin D

  title={Fighting infections with vitamin D},
  author={Michael Zasloff},
  journal={Nature Medicine},
388 VOLUME 12 | NUMBER 4 | APRIL 2006 NATURE MEDICINE vector. The vector used in the CGD study had much higher transcriptional activity in HSPCs than the vector used in most other trials7. Although this strong activity probably allowed better reconstitution of the NADPH enzyme activity, it also may have provided a greater capacity to transactivate cellular genes at the integration site, and thus a higher chance of oncogene activation. The vector could also possibly confer some specificity to… CONTINUE READING


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