Fifty years of the Hodgkin-Huxley era

  title={Fifty years of the Hodgkin-Huxley era},
  author={M. Piccolino},
  journal={Trends in Neurosciences},
  • M. Piccolino
  • Published 2002
  • Medicine, Biology
  • Trends in Neurosciences
Modern neuroscientists are accustomed to the detailed information on the structure and function of membrane ion channels that can be obtained by the combination of molecular biology, crystallography and patch-clamp recordings. It can be difficult for us to appreciate how hard it was for humankind to realize that physical events underlie nervous function and, moreover, to appreciate how long it took to devise a realistic model for the generation and propagation of the nerve impulse. 

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