Fiftieth anniversary of aldosterone: from discovery to cardiovascular therapy.

@article{Tan2004FiftiethAO,
  title={Fiftieth anniversary of aldosterone: from discovery to cardiovascular therapy.},
  author={L B Tan and Dominik Schlosshan and Diane Barker},
  journal={International journal of cardiology},
  year={2004},
  volume={96 3},
  pages={321-33}
}
Half a century after the elucidation of its molecular structure, aldosterone is generating the greatest interest, not in the fields of endocrinology or renal medicine but in cardiology-where aldosterone over-activation is now perceived as detrimental in heart failure (HF) and ischaemic heart disease. Clinically, excess aldosterone is associated with higher… CONTINUE READING