Fifteen cases of t(1;19)(q23;p13.3) identified in an Australian series of 122 children and 80 adults with acute lymphoblastic leukemia.

@article{Sharma2001FifteenCO,
  title={Fifteen cases of t(1;19)(q23;p13.3) identified in an Australian series of 122 children and 80 adults with acute lymphoblastic leukemia.},
  author={P. Sharma and N. Watson and M. Sartor and G. McCowage and A. Smith},
  journal={Cancer genetics and cytogenetics},
  year={2001},
  volume={124 2},
  pages={
          132-6
        }
}
  • P. Sharma, N. Watson, +2 authors A. Smith
  • Published 2001
  • Biology, Medicine
  • Cancer genetics and cytogenetics
  • The t(1;19)(q23;p13) has been reported in up to 6% of cytogenetically abnormal cases of acute lymphoblastic leukaemia (ALL), associated with a pre-B-ALL phenotype. In the 5-year period 1995-1999, we detected t(1;19) in 13 children and 2 adults with newly diagnosed ALL. This represented 10% of pediatric and 2.5% of adult diagnostic ALL samples successfully cultured in one center during this time. There were 9 males and 6 females. The mean age at diagnosis for the 13 children was 6.5 years (range… CONTINUE READING
    8 Citations
    Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia
    • 43
    • PDF
    Karyotypic evolution: cytogenetics follow-up study in childhood acute lymphoblastic leukemia.
    • 10
    • PDF
    Hypodiploidy of 37 chromosomes in an adult patient with acute lymphoblastic leukemia.
    • 6
    Constitutional chromosome aberrations as pathogenetic events in hematologic malignancies.
    • J. Welborn
    • Biology, Medicine
    • Cancer genetics and cytogenetics
    • 2004
    • 34
    • Highly Influenced
    Acknowledgments / The Authors

    References

    SHOWING 1-10 OF 18 REFERENCES
    Clinical significance of translocation t(1;19) in childhood acute lymphoblastic leukemia in the context of contemporary therapies: a report from the Children's Cancer Group.
    • F. Uckun, M. Sensel, +9 authors N. Heerema
    • Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 1998
    • 142
    Frequency of trisomy 15 and loss of the Y chromosome in adult leukemia.
    • 18
    A case of chronic myelomonocytic leukemia with isochromosome 14q.
    • 9