Field performance of engineered male mosquitoes

  title={Field performance of engineered male mosquitoes},
  author={Angela F Harris and Derric Nimmo and A. McKemey and N. Kelly and S. Scaife and C. Donnelly and C. Beech and W. Petrie and L. Alphey},
  journal={Nature Biotechnology},
  • Angela F Harris, Derric Nimmo, +6 authors L. Alphey
  • Published 2011
  • Biology, Medicine
  • Nature Biotechnology
  • Dengue is the most medically important arthropod-borne viral disease, with 50–100 million cases reported annually worldwide. [...] Key Method We report data from the first open-field trial involving a strain of engineered mosquito. We demonstrated that genetically modified male mosquitoes, released across 10 hectares for a 4-week period, mated successfully with wild females and fertilized their eggs. These findings suggest the feasibility of this technology to control dengue by suppressing field populations of…Expand Abstract
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