FieF (YiiP) from Escherichia coli mediates decreased cellular accumulation of iron and relieves iron stress

@article{Grass2004FieFF,
  title={FieF (YiiP) from Escherichia coli mediates decreased cellular accumulation of iron and relieves iron stress},
  author={Gregor Grass and Markus Otto and Beate Fricke and Christopher J. Haney and Christopher Rensing and Dietrich H Nies and Doreen Munkelt},
  journal={Archives of Microbiology},
  year={2004},
  volume={183},
  pages={9-18}
}
The Escherichia coli yiiP gene encodes an iron transporter, ferrous iron efflux (FieF), which belongs to the cation diffusion facilitator family (CDF). Transcription of fieF correlated with iron concentration; however, expression appeared to be independent of the ferrous iron uptake regulator Fur. Absence of FieF led to decreased growth of E. coli cells in complex growth medium but only if fur was additionally deleted. The presence of EDTA was partially able to relieve this growth deficiency… CONTINUE READING

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