Fidaxomicin for treatment of Clostridium difficile infection in clinical practice: a prospective cohort study in a French University Hospital

@article{Pichenot2017FidaxomicinFT,
  title={Fidaxomicin for treatment of Clostridium difficile infection in clinical practice: a prospective cohort study in a French University Hospital},
  author={Marie Pichenot and R H{\'e}quette-Ruz and R{\'e}mi Le Guern and Bruno Grandbastien and Cl{\'e}ment Charlet and Fr{\'e}d{\'e}ric Wallet and Sophie Schiettecatte and Fanny Loeuillet and Benoit Guery and Tatiana Kat{\'e}rina Galperine},
  journal={Infection},
  year={2017},
  volume={45},
  pages={425-431}
}
PurposeTwo randomized controlled trials (RCTs) showed the non-inferiority of fidaxomicin compared with vancomycin for Clostridium difficile infection (CDI) treatment and its superiority regarding recurrence rate. The aim of this study was to evaluate fidaxomicin’s efficacy in clinical practice.MethodsThis single-center prospective cohort study included hospitalized patients treated with fidaxomicin for CDI. Demographic, clinical and biological data were collected. Primary outcome was efficacy… CONTINUE READING
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