Ficus carica; isolation and quantification of the photoactive components *

  title={Ficus carica; isolation and quantification of the photoactive components
  author={Shukrallah Zaynoun and B. G. Aftimos and Lanja A. Ali and K. K. Tenekjian and U. Khalide and Amal. K. Kurban},
  journal={Contact Dermatitis},
The presence and levels of furocoumarins in several parts of Ficus carica including the milky sap, were investigated. The results show that psoralen and bergapten are the only significant photoactive compounds, and are present in appreciable quantities in the leaf and shoot sap but are not detected in the fruit or its sap. These compounds are more concentrated in the leaf sap compared to the shoot sap. The psoralen levels are several times higher than those of bergapten. Lower concentrations of… 

The bergapten content of garden parsley and its significance in causing cutaneous photosensitization

The quantity of bergapten that can be ingested during a regular meal containing parsley is approximately 0·5–0·8 mg, and this amount is considered negligible in causing cutaneous photosensitivity following oral administration of the compound.

Phytophotodermatitis due to Ficus carica.

A case of phytophotodermatitis after contact with fig fruits and leaves was presented, and the vesicular dermatitis was primarily located in areas of vitiligo.

Identification and Quantification of Furanocoumarins in Stem Bark and Wood of Eight Algerian Varieties of Ficus carica by RP-HPLC-DAD and RP-HPLC-DAD-MS

Psoralen and bergapten concentrations were higher in the wood than in the stem bark, and most of the dark fruited fig trees produce these two coumarins more than the green ones.

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Ficus carica L. (Moraceae)

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Contact Dermatitis from Ficus carica

Three patients showed positive reactions to the extract of cut leaves and 8-methoxypsoralen down to a concentration of 0.0001%.

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Phytophotodermatitis caused by Ficus pumila

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Defence mechanisms of Ficus: pyramiding strategies to cope with pests and pathogens

This review presents an overview of physical and chemical defence strategies of Ficus species and discusses how these complementary mechanisms enable effective and flexible adaptation to numerous hostile environments.



A study of oil of bergamot and its importance as a phototoxic agent

The phototoxicity of bergapten was found to be nearly the same as that of xanthotoxin (8‐MOP) in tests on human skin.

A study of oil of bergamot and its importance as a phototoxic agent

The reaction was affected by a range of factors such as the vehicle (PMF or ethanol), the concentration of ethanol in the vehicle, the skin site, the interval between application of the psoralen and irradiation, the hydration of the skin, and the degree of natural or sun‐induced pigmentation.


  • F. Daniels
  • Medicine
    The Journal of investigative dermatology
  • 1965
The method described in this paper is a simple microbiological method for the presumptive identification of plants or plant materials possessing photosensitizing properties of the psoralen type.

Phyto-photo dermatitis.

  • A. Kelly
  • Art
    The Ulster medical journal
  • 1969
ImagesFig. 1Fig. 2Fig. 3

Berloque dermatitis – A continuing cosmetic problem

Despite the decline in the incidence of berloque dermatitis during the past decade, milder cases resulting from the presence of relatively small quantities of bergapten in perfumed cosmetics continue