Fibulin-3 may improve vascular health through inhibition of MMP-2/9 and oxidative stress in spontaneously hypertensive rats.

@article{Lin2016Fibulin3MI,
  title={Fibulin-3 may improve vascular health through inhibition of MMP-2/9 and oxidative stress in spontaneously hypertensive rats.},
  author={Zhongwei Lin and Zhihua Wang and Guobiao Li and Bowei Li and Wenlin Xie and Dingcheng Xiang},
  journal={Molecular medicine reports},
  year={2016},
  volume={13 5},
  pages={3805-12}
}
Fibulin-3 has been suggested to function in the remodeling of the extracellular matrix, however its role remains unclear in hypertensive vascular remodeling. In the current study, 10 Wistar-Kyoto (WKY) rats (control group) and 30 spontaneously hypertensive rats (SHRs) were used. SHRs were randomized into three groups: The placebo group, intravenous (I.V… CONTINUE READING