Fibrous nanostructures from the self-assembly of designed repeat protein modules.


Single-protein-chain superhelical filaments are obtained from monomeric repeat proteins by controlling the chemistry and solvent exposure at their terminal interfaces. The assembly was achieved in aqueous solution, at neutral pH value, and at room temperature. The building block was a recombinantly engineered designed tetratricopeptide repeat protein… (More)
DOI: 10.1002/anie.201203795

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