Fibrous meningeal tumours with extensive non-calcifying collagenous whorls and glial fibrillary acidic protein expression: the whorling-sclerosing variant of meningioma.

@article{Haberler2002FibrousMT,
  title={Fibrous meningeal tumours with extensive non-calcifying collagenous whorls and glial fibrillary acidic protein expression: the whorling-sclerosing variant of meningioma.},
  author={Christine Haberler and Christa Jarius and Susanna Lang and K Roessler and Angela Gruber and J. A. Hainfellner and H Budka},
  journal={Neuropathology and applied neurobiology},
  year={2002},
  volume={28 1},
  pages={42-7}
}
Meningiomas comprise a wide range of morphological patterns. We describe unusual fibrous meningeal tumours in two patients, composed of extensive non-calcifying collagenous whorls of varying size, resembling non-calcified psammoma bodies, while interposed tumour cells are sparse. Immunohistochemistry showed expression of S-100, vimentin and glial fibrillary acidic protein, whereas only single tumour cells stained for epithelial membrane antigen. Electron microscopy detected desmosomes or… CONTINUE READING

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