Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).

@article{Norman2011FibrosisAP,
  title={Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).},
  author={Jill T. Norman},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1812 10},
  pages={1327-36}
}
The age on onset of decline in renal function and end-stage renal disease (ESRD) in autosomal polycystic kidney disease (ADPKD) is highly variable and there are currently no prognostic tools to identify patients who will progress rapidly to ESRD. In ADPKD, expansion of cysts and loss of renal function are associated with progressive fibrosis. Similar to the correlation between tubulointerstitial fibrosis and progression of chronic kidney disease (CKD), in ADPKD, fibrosis has been identified as… CONTINUE READING
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