Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome.

  title={Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome.},
  author={Richard P Marshall and Geoff J Bellingan and Suzanne Webb and Anna Puddicombe and Neil Goldsack and Robin J McAnulty and Geoffrey John Laurent},
  journal={American journal of respiratory and critical care medicine},
  volume={162 5},
The fibroproliferative phase of acute respiratory distress syndrome (ARDS) has traditionally been regarded as a late event but recent studies that suggest increased lung collagen turnover within 24 h of diagnosis challenge this view. We hypothesized that fibroproliferation is initiated early in ARDS, characterized by the presence of fibroblast growth factor activity in the lung and would relate to clinical outcome. Patients fulfilling American/European Consensus Committee criteria for ARDS and… CONTINUE READING
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