Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells.

@article{Mdol2015FibronectinPA,
  title={Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells.},
  author={Teresa M{\'o}dol and Natalia Brice and Marina Ruiz de Galarreta and Antonia Garc{\'i}a Garz{\'o}n and Mar{\'i}a J. Iraburu and Juan Jos{\'e} Mart{\'i}nez-Irujo and Mar{\'i}a Jes{\'u}s L{\'o}pez-Zabalza},
  journal={Journal of cellular physiology},
  year={2015},
  volume={230 3},
  pages={
          546-53
        }
}
The turnover of extracellular matrix (ECM) components can generate signals that regulate several cellular functions such as proliferation, differentiation, and apoptosis. During liver injury, matrix metalloproteases (MMPs) production is enhanced and increased levels of peptides derived from extracellular matrix proteins can be generated. Synthetic peptides with sequences present in extracellular matrix proteins were previously found to induce both stimulating and apoptotic effects on several… CONTINUE READING
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