Fibronectin is a survival factor for differentiated osteoblasts.

@article{Globus1998FibronectinIA,
  title={Fibronectin is a survival factor for differentiated osteoblasts.},
  author={Ruth K. Globus and Steven B. Doty and Juli Lull and Ekhson Holmuhamedov and Martin J Humphries and Caroline H. Damsky},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 10)},
  pages={1385-93}
}
The skeletal extracellular matrix produced by osteoblasts contains the glycoprotein fibronectin, which regulates the adhesion, differentiation and function of various adherent cells. Interactions with fibronectin are required for osteoblast differentiation in vitro, since fibronectin antagonists added to cultures of immature fetal calvarial osteoblasts inhibit their progressive differentiation. To determine if fibronectin plays a unique role in fully differentiated osteoblasts, cultures that… CONTINUE READING

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Effects of triiodothyronine on the morphology of cells and matrix , the localization of alkaline phosphatase and the frequency of apoptosis in long - term cultures of MC 3 T 3E 1

  • S. Frisch, H. Francis
  • cells Bone
  • 1997

Effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase and the frequency of apoptosis in long-term cultures of MC3T3-E1 cells

  • N. Fratzl-Zelman, H. Horandner, +4 authors K. Klaushofer
  • 1997
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