Fibronectin expression in the normal and hypertrophic rat heart.

  title={Fibronectin expression in the normal and hypertrophic rat heart.},
  author={W S Mamuya and Peter I. Brecher},
  journal={The Journal of clinical investigation},
  volume={89 2},
We examined changes in the expression of fibronectin during the induction of cardiac hypertrophy by L-triiodothyronine administration and by mineralocorticoid- and salt-induced experimental hypertension. By use of Northern and Western blotting procedures, fibronectin was localized mainly in the atria of normal rat hearts. Atria contained 10- and 5-fold higher relative concentrations of fibronectin mRNA and protein, respectively, compared with ventricles. During the progression of cardiac… CONTINUE READING
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