• Corpus ID: 24333515

Fibromyalgia and autoimmune diseases: the pain behind autoimmunity.

@article{Buskila2008FibromyalgiaAA,
  title={Fibromyalgia and autoimmune diseases: the pain behind autoimmunity.},
  author={Dan Buskila and Piercarlo Sarzi-Puttini},
  journal={The Israel Medical Association journal : IMAJ},
  year={2008},
  volume={10 1},
  pages={
          77-8
        }
}
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TLDR
A retrospective review of patient records in a university-based rheumatology practice was conducted and the Smart Index (SI), a ratio of the sedimentation rate to one-half the patient's age, was developed to characterize each patient's inflammatory response.
Fibromyalgia in human immunodeficiency virus infection.
TLDR
Fibromyalgia in patients with HIV was significantly associated with myalgia and arthralgia, but not with age, duration of HIV infection, stage of HIV disease, or zidovudine therapy.
Severe rheumatoid arthritis (RA), worse outcomes, comorbid illness, and sociodemographic disadvantage characterize ra patients with fibromyalgia.
TLDR
Fibromyalgia exists in a substantial number of patients with rheumatoid arthritis (17.1%), who have more severe RA by subjective and objective measures, greater medical costs, worse outcomes, more comorbidities, sociodemographic disadvantage, and substantially worse quality of life.
Fibromyalgia in systemic lupus erythematosus
TLDR
Fibromyalgia does not correlate with SLE disease activity, but the clinical features of FM in these patients may contribute to a misinterpretation of lupus activity.
Normal production of inflammatory cytokines in chronic fatigue and fibromyalgia syndromes determined by intracellular cytokine staining in short‐term cultured blood mononuclear cells
TLDR
The study indicates that dysregulation of cytokine production by circulating monocytes or non‐monocytic cells (lymphocytes) is not a dominant factor in the pathogenesis of CFS/FMS.
A prospective evaluation of 118 patients with the fibromyalgia syndrome: prevalence of Raynaud's phenomenon, sicca symptoms, ANA, low complement, and Ig deposition at the dermal-epidermal junction.
TLDR
A subset of patients with fibromyalgia may have features suggestive of a systemic connective tissue disorder, including sicca symptoms, positive ANA or low C3, compared to the 83 patients who did not have Raynaud's phenomenon.
Autoantibodies to a 68/48 kDa protein in chronic fatigue syndrome and primary fibromyalgia: a possible marker for hypersomnia and cognitive disorders.
TLDR
The presence of the anti-68/48 kDa protein antibodies in a portion of both CFS and primary FM patients suggests the existence of a common immunological background and may find utility as possible markers for a clinicoserological subset of CFS/FM patients with hypersomnia and cognitive complaints.
Cytokines play an aetiopathogenetic role in fibromyalgia: a hypothesis and pilot study.
TLDR
In patients with FM, increases over time in serum levels and/or PBMC-stimulated activity of soluble factors whose release is stimulated by substance P are found, hypothesized that they may play a role in modulating FM symptoms.
Quality of life in systemic lupus erythematosus: a controlled study.
TLDR
The quality of life (QOL) of patients with systemic lupus erythematosus and patients with primary fibromyalgia was found to be impaired compared with controls and FM adversely affects the QOL.
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