Fibromyalgia: a clinical review.

@article{Clauw2014FibromyalgiaAC,
  title={Fibromyalgia: a clinical review.},
  author={Daniel J. Clauw},
  journal={JAMA},
  year={2014},
  volume={311 15},
  pages={
          1547-55
        }
}
  • D. Clauw
  • Published 16 April 2014
  • Medicine
  • JAMA
IMPORTANCE Fibromyalgia is present in as much as 2% to 8% of the population, is characterized by widespread pain, and is often accompanied by fatigue, memory problems, and sleep disturbances. OBJECTIVE To review the epidemiology, pathophysiology, diagnosis, and treatment of fibromyalgia. EVIDENCE REVIEW The medical literature on fibromyalgia was reviewed from 1955 to March 2014 via MEDLINE and the Cochrane Central Registry of Controlled Trials, with an emphasis on meta-analyses and… 

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Cannabinoids for fibromyalgia.

TLDR
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TLDR
The present recommendations incorporate the new clinical concepts of FM as a clinical construct without any defining physical abnormality or biological marker, characterized by fluctuating, diffuse body pain and the frequent symptoms of sleep disturbance, fatigue, mood and cognitive changes.

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Fibromyalgia is a common musculoskeletal pain disorder associated with mood disorders. Antidepressants, particularly tricyclics, are commonly recommended treatments. Randomized, controlled trials of

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TLDR
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TLDR
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TLDR
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  • Medicine, Psychology
    Pain medicine
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TLDR
Duloxetine has been shown to be an effective and safe treatment for many of the symptoms associated with fibromyalgia, particularly for women, and agents with dual effects on serotonin and norepinephrine appear to have more consistent benefits than selective serotonin antidepressants for the treatment of persistent pain associated with Fibromyalgia.

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TLDR
It is concluded that low-dose naltrexone may be an effective, highly tolerable, and inexpensive treatment for fibromyalgia.
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