Fibroin gene promoter contains a cluster of homeodomain binding sites that interact with three silk gland factors.

@article{Hui1990FibroinGP,
  title={Fibroin gene promoter contains a cluster of homeodomain binding sites that interact with three silk gland factors.},
  author={Chi chung Hui and Kiyoshi Matsuno and Yasuhiro Suzuki},
  journal={Journal of molecular biology},
  year={1990},
  volume={213 4},
  pages={
          651-70
        }
}
By nuclease protection and mobility shift assays, we have shown that the 5' flanking sequence of the Bombyx mori fibroin gene, which is known to be required for a maximal level of transcription in vitro, contains five regions (A to E) that bind protein factors from the posterior silk gland extract. A silk gland-specific factor (SGF-1) and a ubiquitous factor (FBF-A1) were found to interact with the proximal A region, while the related B region can only bind SGF-1. The three distal regions (C, D… CONTINUE READING
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