Fibroin-derived peptides stimulate glucose transport in normal and insulin-resistant 3T3-L1 adipocytes.

@article{Kim2009FibroinderivedPS,
  title={Fibroin-derived peptides stimulate glucose transport in normal and insulin-resistant 3T3-L1 adipocytes.},
  author={Eun-Do Kim and Tsenguun Bayaraa and Eun-jung Shin and Chang-Kee Hyun},
  journal={Biological & pharmaceutical bulletin},
  year={2009},
  volume={32 3},
  pages={
          427-33
        }
}
Fibroin, the protein of silk, and hydrolyzed fibroin have recently been described to enhance insulin sensitivity and glucose metabolism in 3T3-L1 adipocytes. Here, we report that a series of synthetic peptides derived from the fibroin sequence have enhancing effects on glucose transport in normal and insulin-resistant 3T3-L1 cells. We observed that, among several enzymatic hydrolysates of fibroin, the chymotryptic and peptic hydrolysates were significantly more effective than others in… CONTINUE READING

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