Fibrogenesis. IV. Fibrosis and inflammatory bowel disease: cellular mediators and animal models.

@article{Pucilowska2000FibrogenesisIF,
  title={Fibrogenesis. IV. Fibrosis and inflammatory bowel disease: cellular mediators and animal models.},
  author={Jolanta B. Pucilowska and Kristen L. Williams and Pauline Kay Lund},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2000},
  volume={279 4},
  pages={
          G653-9
        }
}
The cellular mediators of intestinal fibrosis and the relationship between fibrosis and normal repair are not understood. Identification of the types of intestinal mesenchymal cells that produce collagen during normal healing and fibrosis is vital for elucidating the answers to these questions. Acute injury may cause normal mesenchymal cells to convert to a fibrogenic phenotype that is not maintained during normal healing but may lead to fibrosis when inappropriately sustained. Proliferation of… CONTINUE READING

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