Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo.

@article{Hartlapp2001FibrocytesIA,
  title={Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo.},
  author={Ingo Hartlapp and Ryo Abe and Rubina W. Saeed and Tina Peng and Wolfgang Voelter and Richard Bucala and Christine N Metz},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2001},
  volume={15 12},
  pages={2215-24}
}
Angiogenesis is an ordered process requiring the inter-play of numerous cellular and humoral factors. Studies over the past 20 years have identified several growth factors, cytokines, and enzymes that promote blood vessel formation. Most have revealed how individual factors promote an angiogenic phenotype in endothelial cells in vitro or contribute to blood vessel formation in vivo. However, the fundamental question that remains unanswered is how the cellular microenvironment contributes to… CONTINUE READING