Fibroblasts of an acrogeria patient produce normal amounts of type I and III collagen.

@article{BrucknerTuderman1987FibroblastsOA,
  title={Fibroblasts of an acrogeria patient produce normal amounts of type I and III collagen.},
  author={Leena Bruckner-Tuderman and Andreas Vogel and Urs W. Schnyder},
  journal={Dermatologica},
  year={1987},
  volume={174 4},
  pages={157-65}
}
An 11-year-old patient with clinically typical acrogeria is presented. She had wrinkled 'old-appearing' acral skin, thin skin on the whole integument, grooved tip of nose, mottled hyperpigmentation of fold regions and thickened dystrophic toe nails. Histologically, the epidermis was flattened, dermis thinned and the connective tissue densely packed with… CONTINUE READING