Fibroblast involvement in soft connective tissue calcification

  title={Fibroblast involvement in soft connective tissue calcification},
  author={Ivonne Pasquali Ronchetti and Federica Boraldi and Giulia Annovi and Paolo Cianciulli and Daniela Quaglino},
  booktitle={Front. Genet.},
Soft connective tissue calcification is not a passive process, but the consequence of metabolic changes of local mesenchymal cells that, depending on both genetic and environmental factors, alter the balance between pro- and anti-calcifying pathways. While the role of smooth muscle cells and pericytes in ectopic calcifications has been widely investigated… CONTINUE READING