Fibroblast growth factor receptor-4 splice variants cause deletion of a critical tyrosine.

@article{Heumen1999FibroblastGF,
  title={Fibroblast growth factor receptor-4 splice variants cause deletion of a critical tyrosine.},
  author={Walter R A Van Heumen and Christina Claxton and James Pickles},
  journal={IUBMB life},
  year={1999},
  volume={48 1},
  pages={73-8}
}
We have identified two novel isoforms of fibroblast growth factor receptor-4 (FGFR4). They result from alternative splicing of intron 17. Two transcripts, both slightly larger than the one coding for the known mouse FGFR4, are generated. The shortest (FGFR4-17a) includes the 31-most 3'-nucleotides of intron 17; the longest (FGFR4-17b) includes all 114 nucleotides of intron 17. Translation of the FGFR4-17a and FGFR4-17b splice variants predicts that both novel putative FGFR4 isoforms have a… CONTINUE READING