Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy.

@article{Wang2002FibroblastGF,
  title={Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy.},
  author={Fen Wang and Kerstin McKeehan and Chundong Yu and Wallace L. Mckeehan},
  journal={Cancer research},
  year={2002},
  volume={62 6},
  pages={
          1898-903
        }
}
Dissection of processes that promote the slow progression to malignancy from those that drive the malignant phenotype, once acquired, is important for identification of molecular targets for rational design of dietary and pharmaceutical intervention to hold premalignant cancer in check. In adult parenchymal organs, fibroblast growth factor receptor (FGFR) kinase isotypes are partitioned between stroma and epithelium, respectively, and mediate communication between the two compartments to… CONTINUE READING

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