Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing.

@article{Tillman2016FibroblastGF,
  title={Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing.},
  author={Brittny N Tillman and Megan Yanik and Andrew C. Birkeland and Chia-Jen Liu and Daniel H. Hovelson and Andi K. Cani and Nallasivam Palanisamy and Shannon L. Carskadon and Thomas E. Carey and Carol R. Bradford and Scott Arthur Tomlins and Jonathan McHugh and Matthew E Spector and J. Chad Brenner},
  journal={Head & neck},
  year={2016},
  volume={38 Suppl 1},
  pages={E1646-52}
}
BACKGROUND Targeted sequencing of patients with epidemiologically low-risk (ELR) head and neck squamous cell carcinoma (HNSCC) could help identify novel drivers or lost suppressors leading to precision medicine protocols and improved survival rates. METHODS A patient with ELR-HNSCC was selected for targeted sequencing. We then assessed next generation sequencing cohorts from the Oncomine Powertool Database, which contains pan-cancer data from The Cancer Genome Atlas (TCGA). RESULTS Targeted… CONTINUE READING