Fibroblast growth factor 21 night watch: advances and uncertainties in the field.

@article{Kharitonenkov2017FibroblastGF,
  title={Fibroblast growth factor 21 night watch: advances and uncertainties in the field.},
  author={Alexei Kharitonenkov and Richard D DiMarchi},
  journal={Journal of internal medicine},
  year={2017},
  volume={281 3},
  pages={
          233-246
        }
}
Fibroblast growth factor (FGF) 21 belongs to a hormone-like subgroup within the FGF superfamily. The members of this subfamily, FGF19, FGF21 and FGF23, are characterized by their reduced binding affinity for heparin that enables them to be transported in the circulation and function in an endocrine manner. It is likely that FGF21 also acts in an autocrine… CONTINUE READING