Fibroblast growth factor 21 facilitates peripheral nerve regeneration through suppressing oxidative damage and autophagic cell death

@inproceedings{Lu2018FibroblastGF,
  title={Fibroblast growth factor 21 facilitates peripheral nerve regeneration through suppressing oxidative damage and autophagic cell death},
  author={Yingfeng Lu and Rui Li and Junyi Zhu and Yanqing Wu and Duohui Li and Lupeng Dong and Yiyang Li and Xin Wen and Fangzheng Yu and Hongyu Zhang and Xiao Ni and Shenghu Du and Xiaokun Li and Jian Xiao and Jian Wang},
  booktitle={Journal of cellular and molecular medicine},
  year={2018}
}
Seeking for effective drugs which are beneficial to facilitating axonal regrowth and elongation after peripheral nerve injury (PNI) has gained extensive attention. Fibroblast growth factor 21 (FGF21) is a metabolic factor that regulates blood glucose and lipid homeostasis. However, there is little concern for the potential protective effect of FGF21 on nerve regeneration after PNI and revealing related molecular mechanisms. Here, we firstly found that exogenous FGF21 administration remarkably… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 84 REFERENCES

Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells.

  • Molecular and cellular biology
  • 2007
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

The origin and development of glial cells in peripheral nerves

  • Nature Reviews Neuroscience
  • 2005
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

FGF21 protects the blood‐brain barrier by upregulating PPARgamma via FGFR1/beta‐Klotho following traumatic brain injury

J Chen, J Hu, H Liu
  • J Neurotrauma
  • 2018
VIEW 2 EXCERPTS

Similar Papers

Loading similar papers…