Fibroblast growth factor 21 as a possible endogenous factor inhibits apoptosis in cardiac endothelial cells.

@article{L2010FibroblastGF,
  title={Fibroblast growth factor 21 as a possible endogenous factor inhibits apoptosis in cardiac endothelial cells.},
  author={Yun L{\"u} and Jinghua Liu and Li-ke Zhang and Jie Du and Xiang-jun Zeng and Gang Hao and Ji Huang and Dong-hui Zhao and Guo-zhong Wang and Ying-chuan Zhang},
  journal={Chinese medical journal},
  year={2010},
  volume={123 23},
  pages={
          3417-21
        }
}
BACKGROUND Fibroblast growth factor 21 (FGF21) is a new member of FGF super family that is an important endogenous regulator for systemic glucose and lipid metabolism. This study aimed to explore whether FGF21 reduces atherosclerotic injury and prevents endothelial dysfunction as an independent protection factor. METHODS The present study was designed to investigate the changes of FGF21 levels induced by oxidized-low density lipoprotein (ox-LDL), and the changes of apoptosis affected by… CONTINUE READING

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