Fibroblast growth factor 20 (FGF20) polymorphism is a risk factor for Parkinson's disease in Chinese population.

@article{Pan2012FibroblastGF,
  title={Fibroblast growth factor 20 (FGF20) polymorphism is a risk factor for Parkinson's disease in Chinese population.},
  author={Jing Pan and Hui Li and Ying Wang and Jianfang Ma and Jin Zhang and Gang Wang and Jun Liu and Xi-jin Wang and Qin Xiao and S Chen},
  journal={Parkinsonism & related disorders},
  year={2012},
  volume={18 5},
  pages={629-31}
}
The etiology of Parkinson's disease (PD) is not well established. Genetic variation in fibroblast growth factor 20 (FGF20) might influence the risk of PD occurrence and development. In this study, Two DNA polymorphisms at genetic variation in FGF20, rs2720208 (C/T) and rs1721100 (C/G), were genotyped by direct sequencing in Han Chinese population, including 394 PD patients and 383 healthy controls. Statistical analyses revealed that for rs1721100 (C/G) polymorphism, there were significant… CONTINUE READING