Fibroblast growth factor-2 promotes axon branching of cortical neurons by influencing morphology and behavior of the primary growth cone.

@article{Szebenyi2001FibroblastGF,
  title={Fibroblast growth factor-2 promotes axon branching of cortical neurons by influencing morphology and behavior of the primary growth cone.},
  author={Gy{\"o}rgyi Szebenyi and Erik W. Dent and Johnatan L Callaway and Chad W. Seys and H J L{\"u}th and Katherine Kalil},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2001},
  volume={21 11},
  pages={3932-41}
}
Interstitial branching is an important mechanism for target innervation in the developing CNS. A previous study of cortical neurons in vitro showed that the terminal growth cone pauses and enlarges in regions from which interstitial axon branches later develop (Szebenyi et al., 1998). In the present study, we investigated how target-derived signals affect… CONTINUE READING