Fibroblast growth factor 1: a key regulator of human adipogenesis.

  title={Fibroblast growth factor 1: a key regulator of human adipogenesis.},
  author={Louise J. Hutley and Wenda Shurety and Felicity Newell and Ross McGeary and Nicole C Pelton and Jennifer V. Grant and Adrian C. Herington and Donald Cameron and Jon Whitehead and Johannes B. Prins},
  volume={53 12},
Obesity, with its related problems, is recognized as the fastest growing disease epidemic facing the world, yet we still have limited insight into the regulation of adipose tissue mass in humans. We have previously shown that adipose-derived microvascular endothelial cells (MVECs) secrete a factor(s) that increases proliferation of human preadipocytes. We now demonstrate that coculture of human preadipocytes with MVECs significantly increases preadipocyte differentiation, evidenced by… CONTINUE READING
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Adipose tissue

  • LJ Hutley, FS Newell, SJ Suchting, JB Prins
  • In Primary Mesenchymal Cells,
  • 2001

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