Fibroblast growth factor (FGF)-1, FGF2, FGF7 and FGF receptors are uniformly expressed in trophoblast giant cells during restricted trophoblast invasion in cows.

@article{Pfarrer2006FibroblastGF,
  title={Fibroblast growth factor (FGF)-1, FGF2, FGF7 and FGF receptors are uniformly expressed in trophoblast giant cells during restricted trophoblast invasion in cows.},
  author={Christiane Pfarrer and Sebastian Weise and Bajram Berisha and Dieter Schams and Rudolf Leiser and Bernd Hoffmann and Gerhard Schuler},
  journal={Placenta},
  year={2006},
  volume={27 6-7},
  pages={
          758-70
        }
}
The bovine placenta is characterized by a limited invasion of trophoblast giant cells (TGC). In contrast to mononuclear trophoblast cells (MTC), TGC are non-polarized cells, which migrate and fuse with single uterine epithelial cells throughout gestation. Fibroblast growth factors (FGF) were shown to be associated with the migratory activity of cells, cell differentiation and angiogenesis, and due to its localization in trophoblast cells were proposed as important regulating factors in… CONTINUE READING

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