Fibroblast-fibronectin patterning and network formation in 3D fibrin matrices.

Abstract

PURPOSE We previously reported that fibroblasts migrating within 3-D collagen matrices move independently, whereas fibroblasts within 3-D fibrin matrices form an interconnected network. Similar networks have been identified previously during in vivo corneal wound healing. In this study, we investigate the role of fibronectin in mediating this mechanism of… (More)
DOI: 10.1016/j.matbio.2017.06.001

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