Fibroblast apoptosis in a patient affected by lamellar ichthyosis.


BACKGROUND Lamellar ichthyosis (LI) is a congenital recessive skin disorder characterized by generalized scaling and hyperkeratosis. The pathology may be caused by mutations in transglutaminase 1 (TGM1) gene that encodes an enzyme critical for terminally differentiating keratinocytes. Because of evidences that transglutaminase enzymes are involved in… (More)
DOI: 10.1111/j.1600-0560.2008.01078.x

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