Fibroblast Growth Factor 21-Metabolic Role in Mice and Men.

@article{Staiger2017FibroblastGF,
  title={Fibroblast Growth Factor 21-Metabolic Role in Mice and Men.},
  author={Harald Staiger and Michaela Keuper and Lucia Berti and Martin Hrabě de Angelis and Hans-Ulrich H{\"a}ring},
  journal={Endocrine reviews},
  year={2017},
  volume={38 5},
  pages={
          468-488
        }
}
Since its identification in 2000, the interest of scientists in the hepatokine fibroblast growth factor (FGF) 21 has tremendously grown, and still remains high, due to a wealth of very robust data documenting this factor's favorable effects on glucose and lipid metabolism in mice. For more than ten years now, intense in vivo and ex vivo experimentation addressed the physiological functions of FGF21 in humans as well as its pathophysiological role and pharmacological effects in human metabolic… CONTINUE READING
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