Fibrinolysis Autographs

@article{Todd1958FibrinolysisA,
  title={Fibrinolysis Autographs},
  author={A. Todd},
  journal={Nature},
  year={1958},
  volume={181},
  pages={495-496}
}
  • A. Todd
  • Published 1958
  • Medicine
  • Nature
  • Permin and Astrup used a plate method of demonstrating fibrinolytic activity1,2. This technique can be applied histologically. A thin layer of fibrin is made on a microslide by adding a drop or two of fibrinogen to a film of thrombin on the glass. When the fibrin layer has formed, a section of fresh or alcohol-fixed tissue cut on the freezing microtome is applied to its surface and the preparation incubated at 37° C. After 30–60 min. patches of digestion of the fibrin appear in relation to… CONTINUE READING
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