Fibrinogen plasma levels as a marker of thrombin activation: new insights on the role of fibrinogen as a cardiovascular risk factor.

@article{Ceriello1994FibrinogenPL,
  title={Fibrinogen plasma levels as a marker of thrombin activation: new insights on the role of fibrinogen as a cardiovascular risk factor.},
  author={Antonio Ceriello and Mario Pirisi and Roberta Giacomello and Giuliana Stel and Edmondo Falleti and Enrico Motz and Salvador Lizzio and Fabio Gonano and Ettore Bartoli},
  journal={Thrombosis and haemostasis},
  year={1994},
  volume={71 5},
  pages={593-5}
}
Fibrinogen has recently emerged as a major risk factor for atherothrombosis. However, the pathophysiologic mechanism linking high fibrinogen concentration to cardiovascular disease is unclear. In this study 136 subjects (75 males, 61 females, age 51.7 +/- 14.4 years, mean +/- standard deviation, range 17-82) were tested for total and HDL-cholesterol, total triglycerides, apolipoprotein AI, apolipoprotein B, fibrinogen, prothrombin fragment and D-dimer. Moreover, 5 subjects who had… CONTINUE READING
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