Fibrinogen measurement in cardiac surgery with cardiopulmonary bypass: analysis of repeatability and agreement of Clauss method within and between six different laboratories.

@article{Solomon2014FibrinogenMI,
  title={Fibrinogen measurement in cardiac surgery with cardiopulmonary bypass: analysis of repeatability and agreement of Clauss method within and between six different laboratories.},
  author={Cristina Solomon and Ekaterina Baryshnikova and Armando Tripodi and Christoph Johannes Schlimp and Herbert Sch{\"o}chl and Janne Cadamuro and Dag Winstedt and Lars M. Asmis and Matteo Ranucci},
  journal={Thrombosis and haemostasis},
  year={2014},
  volume={112 1},
  pages={
          109-17
        }
}
Plasma fibrinogen concentration is important for coagulopathy assessment, and is most commonly measured using the Clauss method. Several factors, including device type and reagent, have been shown to affect results. The study objective was to evaluate performance and repeatability of the Clauss method and to assess differences between measurements performed during and after cardiopulmonary bypass (CPB), by testing plasma samples from patients undergoing cardiac surgery with CPB. Samples were… CONTINUE READING
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