Fibrinogen level deteriorates before other routine coagulation parameters and massive transfusion in the early phase of severe trauma: a retrospective observational study.

@article{Hayakawa2015FibrinogenLD,
  title={Fibrinogen level deteriorates before other routine coagulation parameters and massive transfusion in the early phase of severe trauma: a retrospective observational study.},
  author={Mineji Hayakawa and Satoshi Gando and Yuichi Ono and Takeshi Wada and Yuichiro Yanagida and Atsushi Sawamura},
  journal={Seminars in thrombosis and hemostasis},
  year={2015},
  volume={41 1},
  pages={35-42}
}
In trauma, hemostatic functions should be maintained appropriately to prevent massive bleeding. This study elucidated the time-dependent changes in platelet count and coagulation variables, and the effects of disseminated intravascular coagulation (DIC) on these changes during the early phase of trauma. Trauma patients with an injury severity score ≥16 were enrolled. The critical levels of platelet count and coagulation variables were defined according to recent trauma guidelines. Massive… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 41 references

hemostasis: a primary hemostatic target for the management of acquired bleeding

CJ Schlimp, H. Schöchl
Anesth Analg • 2014

Administration of fi brinogen concentrate in exsanguinating trauma patients is associatedwith improved survival at 6 hours but not at discharge

A Wafaisade, R Lefering
J Trauma Acute Care Surg • 2013

Cryoprecipitate use in the PROMMTT study.

The journal of trauma and acute care surgery • 2013

Trauma Registry of DGU. Administration of fibrinogen concentrate in exsanguinating trauma patients is associatedwith improved survival at 6 hours but not at discharge

A Wafaisade, R Lefering, MaegeleM
J Trauma Acute Care Surg • 2013

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