Fibrinogen level as a surrogate for the outcome of thrombolytic therapy using tissue plasminogen activator for acute lower extremity intravascular thrombosis.

@article{Skeik2013FibrinogenLA,
  title={Fibrinogen level as a surrogate for the outcome of thrombolytic therapy using tissue plasminogen activator for acute lower extremity intravascular thrombosis.},
  author={Nedaa Skeik and Colton C Gits and Eduardo Ehrenwald and Andrew H. Cragg},
  journal={Vascular and endovascular surgery},
  year={2013},
  volume={47 7},
  pages={519-23}
}
PURPOSE Monitoring of fibrinogen level is used to predict bleeding during lower extremity tissue plasminogen activator (tPA) infusions for peripheral arterial or venous thrombolysis. This practice is not fully addressed in the literature. MATERIALS AND METHODS We retrospectively reviewed fibrinogen levels and studied bleeding rate from charts of patients who underwent lower extremity tPA infusions at a single hospital from January 2010 to May 2012. RESULTS The rate of thrombolytic success… CONTINUE READING