Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: study protocol for a randomised controlled trial

@inproceedings{Aawar2015FibrinogenCV,
  title={Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: study protocol for a randomised controlled trial},
  author={Nadine Aawar and Raza Alikhan and Daniel Bruynseels and Rebecca L Cannings-John and Rachel E Collis and John R Dick and Christopher Elton and Roshan Fernando and Judith E. Hall and Kerenza Hood and Nicki Lack and Shuba Mallaiah and Helena Maybury and Jacqueline Nuttall and Shantini Paranjothy and Rachel Rayment and Alexandra Rees and Julia Sanders and J Townson and Andrew D Weeks and Peter Collins},
  booktitle={Trials},
  year={2015}
}
BACKGROUND Postpartum haemorrhage (PPH) is a major cause of maternal morbidity. Bleeding is caused by a combination of physical causes, such as failure of the uterus to contract or operations, and is made worse by impairment of the blood clotting system. A number of studies have shown that low levels of the blood clotting factor fibrinogen are associated with progression of bleeding, the need for invasive interventions and transfusions of red blood cells and fresh frozen plasma (FFP). This… CONTINUE READING
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fact sheet 348

  • World Health Organisation. Maternal mortality
  • 2012; Available from: http://www.who.int…
  • 2015
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