Fibrinogen as a key regulator of inflammation in disease

@article{Davalos2011FibrinogenAA,
  title={Fibrinogen as a key regulator of inflammation in disease},
  author={D. Davalos and K. Akassoglou},
  journal={Seminars in Immunopathology},
  year={2011},
  volume={34},
  pages={43-62}
}
  • D. Davalos, K. Akassoglou
  • Published 2011
  • Medicine
  • Seminars in Immunopathology
  • The interaction of coagulation factors with the perivascular environment affects the development of disease in ways that extend beyond their traditional roles in the acute hemostatic cascade. Key molecular players of the coagulation cascade like tissue factor, thrombin, and fibrinogen are epidemiologically and mechanistically linked with diseases with an inflammatory component. Moreover, the identification of novel molecular mechanisms linking coagulation and inflammation has highlighted… CONTINUE READING
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