Fibrinogen as a hemostatic agent.

@article{Srensen2012FibrinogenAA,
  title={Fibrinogen as a hemostatic agent.},
  author={Benny M{\o}ller S{\o}rensen and Ole Halfdan Larsen and Catherine J. Rea and Mariann Tang and J. H. Michael Foley and Christian Fenger-Eriksen},
  journal={Seminars in thrombosis and hemostasis},
  year={2012},
  volume={38 3},
  pages={
          268-73
        }
}
Coagulation factor I (fibrinogen) plays an essential role in the hemostatic system by bridging activated platelets and being the key substrate for thrombin in establishing a consolidating fibrin network. Fibrinogen is synthesized in the liver and the plasma concentration is 1 to 5-4.0 g/L. During recent 10 years, fibrinogen has been recognized to play an important role in controlling hemorrhage. Dilutional coagulopathy induced by colloid plasma expanders is characterized by fibrinogen… CONTINUE READING
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