Fibrinogen adsorption and platelet lysis characterization of fluorinated surface-modified polyetherurethanes.

@article{Massa2007FibrinogenAA,
  title={Fibrinogen adsorption and platelet lysis characterization of fluorinated surface-modified polyetherurethanes.},
  author={Tali Massa and W Glenn McClung and Meng Ling Yang and Jason Chak-Shing Ho and John Law Brash and J Paul Santerre},
  journal={Journal of biomedical materials research. Part A},
  year={2007},
  volume={81 1},
  pages={178-85}
}
A polyetherurethane (PU) was modified using fluorinated surface-modifying macromolecules (SMMs). A double radiolabel method was used simultaneously to measure the number of adhered platelets ((51)Cr) and the quantity of adsorbed Fg ((125)I), in a cone-and-plate instrument. The objectives were to determine if adsorbed Fg levels correlated to platelet adhesion on the surfaces, and to assess if any reductions in platelet adhesion for the SMM-treated surfaces resulted from surface-induced platelet… CONTINUE READING

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